Skip to main content

Table 1 Inhibitory effects of EPA on lipid accumulation in 3T3-L1 adipocytes

From: Eicosapentaenoic acid increases lipolysis through up-regulation of the lipolytic gene expression and down-regulation of the adipogenic gene expression in 3T3-L1 adipocytes

Treatment (h)

Lipid accumulation (%)

Control

EPA

0

100.0 ± 9.9a

100.0 ± 9.6a

3

98.3 ± 6.3a, b

89.4 ± 2.a, b

6

93.8 ± 9.5a, b

88.1 ± 1.1a, b

12

94.5 ± 9.6a, b

83.1 ± 12.5a, b

24

93.8 ± 5.0a, b

76.0 ± 2.9b

  1. The 3T3-L1 adipocytes were incubated in serum-free medium with 300 μM of EPA for 3, 6, 12, or 24 h. The values were calculated as a percentage of lipid content of the control cells without EPA treatment and expressed as the mean ± SD (n = 5). Values with different superscript letters are significantly different at P < 0.05 by Tukey’s test
Back to article page

Genes & Nutrition

ISSN: 1865-3499

Contact us