From: Intestinal microbiota in human health and disease: the impact of probiotics
Study material | Population | Analytical methods | References |
---|---|---|---|
Atopic and allergic diseases | |||
Faeces | 27 Allergic children 36 Non-allergic children | Conventional culturing | Björkstén et al. (1999) |
Faeces (5 time points) | 18 Infants who developed allergy 26 Infants who remained non-allergic | Conventional culturing | Björkstén et al. (2001) |
Faeces (2 time points) | 76 Infants at high risk for atopic disease | Conventional culturing FISH | Kalliomäki et al. (2001) |
Faeces (2/3 time points) | 27 Infants with atopic dermatitis 10 Infants without atopic dermatitis | Conventional culturing FISH | Kirjavainen et al. (2001) |
Faeces | 30 Children with atopic dermatitis 68 Children without atopic dermatitis | Conventional culturing | Watanabe et al. (2003) |
Faeces | 957 Infants | qPCR | Penders et al. (2007) |
Faeces | 20 Allergic children 20 Non-allergic children | DGGE | Štšepetova et al. (2007) |
Faeces (3 time points) | 10 Allergic infants 16 Non-allergic infants | qPCR | Suzuki et al. (2007) |
Faeces | 37 Infants with atopic dermatitis 24 Infants without atopic dermatitis | TGGE FISH/flow cytometry | Gore et al. (2008) |
Faeces | 15 Infants who developed atopic dermatitis 20 Infants who remained without atopic dermatitis | T-RFLP TGGE | Wang et al. (2008) |
Faeces (3 time points) | 16 Infants who developed allergy 31 Infants who remained non-allergic | qPCR | Sjögren et al. (2009) |
Autism | |||
Faeces Stomach contents Small intestine contents | 13 Autistic children 8 Non-autistic children | Conventional culturing 16S rRNA gene sequencing | Finegold et al. (2002) |
Faeces | 15 Autistic children 8 Non-autistic children | qPCR | Song et al. (2004) |
Faeces | 58 Autistic children 12 Non-autistic siblings 10 Non-autistic children | FISH | Parracho et al. (2005) |
Faeces | 33 Autistic children 7 Non-autistic siblings 8 Non-autistic children | 454 FLX titanium sequencing (16S) | Finegold et al. (2010) |
Diabetes type 2 | |||
Faeces | 16 Type 2 diabetic patients 12 Non-diabetic individuals | DGGE qPCR | Wu et al. (2010) |
Faeces | 18 Type 2 diabetic patients 18 Non-diabetic individuals | qPCR 454 FLX titanium sequencing (16S) | Larsen et al. (2010) |
Rheumatoid arthritis | |||
Faeces | 51 Patients with early rheumatoid arthritis 50 Patients with fibromyalgia | FISH/flow cytometry | Vaahtovuo et al. (2008) |