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Table 2 Fasting triglyceride levels according to diet intakes, PNPLA3 rs738409 genotype and obesity status

From: The PNPLA3 Ile148Met interacts with overweight and dietary intakes on fasting triglyceride levels

Triglycerides

Range

All

PNPLA3 genotype

Normal weight (BMI ≤ 25)

PNPLA3 genotype

Overweight (BMI > 25)

PNPLA3 genotype

Min–max

CC

CG

GG

P trenda

CC

CG

GG

P trenda

CC

CG

GG

P trenda

Carbohydrates E%

N

 

3,028

1,605

194

 

1,465

780

101

 

1,561

824

93

 

1st tertile

16–44

1.64

1.20, 2.11

1.54

1.10, 2.01

1.45

0.95, 1.95

0.02

1.29

1.13, 1.46

1.21

1.04, 1.38

1.27

1.02, 1.53

0.67

1.73

1.16, 2.31

1.65

1.07, 2.24

1.40

0.74, 2.05

0.04

2nd tertile

44–49

1.59

1.12, 2.10

1.61

1.14, 2.10

1.52

1.02, 2.02

0.56

1.21

1.05, 1.38

1.27

1.10, 1.44

1.31

1.05, 1.57

0.04

1.74

1.16, 2.31

1.70

1.12, 2.29

1.50

0.86, 2.13

0.24

3rd tertile

49–81

1.61

1.14, 2.10

1.60

1.13, 2.10

1.69

1.20, 2.20

0.92

1.28

1.12, 1.44

1.33

1.16, 1.50

1.44

1.17, 1.70

0.22

1.74

1.16, 2.31

1.67

1.09, 2.25

1.72

1.08, 2.36

0.24

P trendb

 

0.63

0.08

0.40

 

0.89

0.02

0.40

 

0.85

0.55

0.13

 

(P interactionb)

    

(0.07)

   

(0.12)

   

(0.51)

Sucrose E%

N

 

3,028

1,605

194

 

1,465

780

101

 

1,561

824

93

 

1st tertile

0.60–6.70

1.61

1.15, 2.10

1.56

1.10, 2.04

1.42

0.92, 1.92

0.15

1.27

1.11, 1.43

1.22

1.05, 1.39

1.26

1.02, 1.50

0.54

1.72

1.14, 2.29

1.68

1.10, 2.27

1.36

0.71, 2.01

0.06

2nd tertile

6.70–9.31

1.61

1.14, 2.10

1.57

1.10, 2.05

1.55

1.05, 2.05

0.31

1.26

1.10, 1.42

1.24

1.07, 1.41

1.24

1.00, 1.49

0.42

1.73

1.15, 2.31

1.67

1.08, 2.25

1.64

1.01, 2.28

0.34

3rd tertile

9.31–38.0

1.62

1.15, 2.10

1.62

1.15, 2.10

1.73

1.22, 2.24

0.34

1.27

1.11, 1.43

1.35

1.18, 1.52

1.61

1.32, 1.89

0.001

1.76

1.18, 2.33

1.68

1.09, 2.26

1.61

0.96, 2.26

0.12

P trendb

 

0.31

0.05

0.06

 

0.42

0.008

0.69

 

0.29

0.57

0.39

 

(P interactionb)

    

(0.07)

   

(0.03)

   

(0.17)

ω-6:ω-3 PUFA ratio

N

 

3,028

1,605

194

 

1,465

780

101

 

1,561

824

93

 

1st tertile

0.60–4.50

1.60

1.12, 2.10

1.52

1.04, 2.00

1.47

1.00, 2.00

0.10

1.23

1.07, 1.39

1.24

1.06, 1.40

1.33

1.07, 1.59

0.19

1.73

1.15, 2.31

1.60

1.01, 2.18

1.42

0.78, 2.05

0.001

2nd tertile

4.50–6.00

1.59

1.12, 2.10

1.64

1.20, 2.11

1.48

1.00, 2.00

0.43

1.22

1.06, 1.38

1.33

1.16, 1.50

1.14

0.83, 1.45

0.10

1.74

1.16, 2.32

1.73

1.15, 2.32

1.54

0.90, 2.18

0.61

3rd tertile

6.00–31.0

1.63

1.20, 2.10

1.56

1.10, 2.03

1.66

1.20, 2.20

0.37

1.31

1.15, 1.47

1.23

1.06, 1.39

1.42

1.19, 1.65

1.00

1.72

1.15, 2.30

1.70

1.10, 2.27

1.73

1.07, 2.38

0.64

P trendb

 

0.04

0.54

0.16

 

0.01

0.55

0.66

 

0.80

0.13

0.48

 

(P interactionb)

    

(0.82)

   

(0.22)

   

(0.08)

  1. aCalculations were made by using the general linear model. Basic model adjusted for age and sex
  2. bMultivariate model adjusted for age, sex, diet method version, season, education, alcohol intake, smoking, total energy intake and leisure time physical activity