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Table 2 Gene annotation enrichment analysis, performed using the DAVID Bioinformatic Resources 6.7, of genes identified as being regulated by the extended fast

From: Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 h fast provides evidence of effects on genes regulating inflammation, apoptosis and energy metabolism

Category

Term

Gene count

% of list

Raw p value

Adjusted p valuea

GOTERM_MF_FAT

Cytokine activity (GO:0005125)

7

16.7

6.96 × 10−6

9.88 × 10−4

SP_PIR_KEYWORDS

Cytokine

6

14.3

3.98 × 10−5

5.87 × 10−3

GOTERM_CC_FAT

Extracellular region part (GO:0044421)

10

23.8

4.23 × 10−4

2.55 × 10−2

GOTERM_CC_FAT

Extracellular space (GO:0005615)

9

21.4

2.18 × 10−4

2.62 × 10−2

INTERPRO

Small chemokine, C-X-C, conserved site (IPR018048)

3

7.1

7.10 × 10−4

3.19 × 10−2

INTERPRO

Small chemokine, C-X-C/Interleukin 8 (IPR002473)

3

7.1

4.77 × 10−4

3.22 × 10−2

GOTERM_BP_FAT

Response to wounding (GO:0009611)

9

21.4

3.88 × 10−5

3.22 × 10−2

PIR_SUPERFAMILY

CXC chemokine (PIRSF002522)

3

7.1

1.22 × 10−3

3.84 × 10−2

  1. aBenjamini and Hochberg adjusted p value