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Table 3 Number of nodes and edges in the complete knowledge-based network and the white adipose tissue reference network (WATRefNet), total and per tissue (i.e., blood, physiology, adipose and PBMC)

From: White adipose tissue reference network: a knowledge resource for exploring health-relevant relations

 

Complete knowledge-based network

Total WATRefNet

Blood

Physiology

Adipose

PBMC

Nodes

 Gene/protein

14,488

4,361

23

0

4,234

104

 Metabolite

12,729

2,349

18

0

2,241

90

 Non-molecular

18

23

5

11

7

0

 miRNA

432

64

0

0

64

0

Total

27,667

6,797

46

11

6,546

194

Edges

 DrugBank

9,494

504

0

0

504

0

 KEGG

195,867

5,682

1

0

5,622

59

 STITCH

76,269

6,973

47

0

6,691

235

 STRING

155,971

17,910

46

0

17,745

119

 TFe

1,929

259

1

0

258

0

 WikiPathways

18,601

2,989

0

0

2,983

6

 MirTarBase

3,597

265

0

0

265

0

 Correlation

0

32

1

28

3

0

Total (merged)

447,174

32,171

95

28

31,645

403

  1. Different resources for edges comprise different edge types (DrugBank: drug–target interactions, KEGG: manually curated metabolic and signaling pathways, STITCH: chemical–protein interactions, STRING: protein–protein interactions and associations, TFe: transcription factor–target interactions, WikiPathways: manually curated metabolic and signaling pathways, MirTarBase: manually curated miRNA–target interactions