Polymorphism in miR-31 and miR-584 binding site in the angiotensinogen gene differentially influences body fat distribution in both sexes

Table 2 Effects of AGT +11525 C/A genotype, sex and obesity on body fat distribution

Parameter of body fat distribution	Obesity a significant factor	Obesity status (if applicable)	Men—effect	Men—p value	Women—effect	Women—p value
Waist circumference	No	NA	CC > CA + AA	0.022	CC < CA + AA	0.109
Hip circumference	Yes	Obese	CC > CA + AA	0.120	CC < CA + AA	0.015
Hip circumference	Yes	Non-obese	–	–	–	–
Skin-fold thickness (triceps)	Yes	Obese	–	–	–	–
Skin-fold thickness (triceps)	Yes	Non-obese	CC < CA + AA	0.064	CC > CA + AA	0.023
Skin-fold thickness (supraspinal)	No	NA	CC > CA + AA	0.022	CC < CA + AA	0.003
Skin-fold thickness (sum)	Yes	Obese	CC > CA + AA	0.081	CC < CA + AA	0.028
Skin-fold thickness (sum)	Yes	Non-obese	–	–	–	–

NA not applicable. Trends with p < 0.15 are listed in the table. Significant effects with p < 0.05 are marked bold. In case of waist–hip ratio, bicipital and subscapular skin-fold thickness, AGT +11525 C/A genotype was not significant factor in the model

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