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Table 2 Relative expression of genes (fold change, Chinese vs. Indian) with known variants between rhesus monkeys of different origin in the prefrontal cortex (PFC), cerebellum (CER), and striatum (STR) (n = 3 per group)

From: Brain xanthophyll content and exploratory gene expression analysis: subspecies differences in rhesus macaque

 

Fold change-PFC

p value

Fold change-CER

p value

Fold change-STR

p value

CCL5

1.07

0.98

1.01

0.99

1.15

0.94

CXCL12

1.45

0.19

1.18

0.61

3.22

0.00058

XCL1

1.43

0.42

0.89

0.77

3.57

0.11

CCR4

1.50

0.67

1.27

0.72

1.19

0.79

CCR1

1.94

0.02

1.46

0.21

1.57

0.07

IL2RA

2.04

0.50

1.89

0.58

1.00

0.98

CD74

2.11

0.0001

1.44

0.09

2.52

0.0000043

CD4

3.69

0.0000001

1.66

0.008

3.59

0.0000006

CD44

−1.08

0.81

−1.12

0.31

1.27

0.38

TLR5

1.06

0.83

−1.20

0.63

1.02

0.94

LTBR

−1.52

0.02

−1.28

0.22

−1.06

0.80

FAS

1.27

0.58

1.24

0.57

−1.39

0.43

MAOA

1.06

0.72

1.03

0.89

1.04

0.86

BCHE

1.13

0.15

1.43

0.12

−1.01

0.99

NOS1

1.06

0.82

1.24

0.25

1.57

0.05

NPY

1.00

0.99

−10.0

0.05

1.18

0.36

PYY

1.08

0.92

1.92

0.65

3.04

0.41

SLC5A7

1.56

0.19

1.67

0.19

1.01

0.95

SLC6A4

1.67

0.67

−3.23

0.27

−1.75

0.69

SNCA

1.21

0.10

1.08

0.63

1.41

0.04

INHBB

−1.11

0.68

−1.08

0.82

1.13

0.68

SIRT1

1.13

0.51

1.08

0.64

1.23

0.34

HTATSF1

1.10

0.35

1.03

0.82

1.13

0.41

STAR

−1.52

0.18

−1.30

0.49

−1.04

0.91

ADRBK2

1.21

0.19

1.11

0.49

1.52

0.08

ITGA4

−1.10

0.74

1.01

0.99

1.80

0.32

SASH1

1.13

0.35

1.21

0.31

1.30

0.12

  1. Fold change calculated by dividing fragments per kilobase of transcript per million mapped reads (FPKM) Chinese origin by FPKM Indian origin. Genes in italics showed a significant difference in expression in at last one brain region. Genes bold were selected for RT-PCR analysis