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Fig. 4 | Genes & Nutrition

Fig. 4

From: SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice

Fig. 4

Representative in situ autoradiographs of mouse brain sections showing serpinA3N expression in a ob/ob mouse on a C57BL/6J background and b lean C57BL/6J mouse. Levels of serpinA3N gene expression in the arcuate nuclei measured by semi-quantitative in situ hybridisation of c db/db on a C57BL/6J background and lean C57BL/6J mice, d ob/ob and lean mice, e ob/ob mice injected with IP vehicle (veh.) or leptin after either 1 or 4 h (h) and f lean mice injected with IP vehicle (veh.) or leptin after either 1 or 4 h (h). *** P < 0.001 (n = 6)

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