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Fig. 8 | Genes & Nutrition

Fig. 8

From: SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice

Fig. 8

a–f In mHypoE-N42 cells, a–c SerpinA3N, IL-6 and TNFα gene expression were all upregulated by leptin and palmitic acid challenge and downregulated by oleic acid. d–f The upregulation of SerpinA3N, IL-6 and TNFα gene expression by palmitic acid was blocked by the NKκB inhibitor BAY11. P < 0.05, ***P < 0.001, **P < 0.01. NS not significant

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