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Table 1 Results of the GenMAPP/MappFinder analysis of pathways affected by red wine polyphenols

From: An integrated bioinformatics approach to improve two-color microarray quality-control: impact on biological conclusions

 

Number of genes changed

Block by block normalisation

 Pathways down-regulated

  Rn_Prostaglandin_synthesis_regulation

13

  Rn_MAPK_signaling_pathway_ KEGG

46

  Rn_Oxidative_Stress

9

  Rn_TGF_Beta_Signaling_Pathway

20

  Rn_Cytokines_and_Inflammatory_Response_Biocarta

15

 Pathways up-regulated

  Rn_G1_to_S_cell_cycle_Reactome

3

  Rn_Cell_cycle_KEGG

4

Global normalisation

 Pathways down-regulated

  Rn_MAPK_signaling_pathway_ KEGG

21

  Rn_TGF-beta-Receptor_NetPath_7

15

 Pathways up-regulated

  Rn_Focal_adhesion_KEGG

5

  Rn_EGFR1_NetPath_4

4

  Rn_Oxidative_Stress

5

  1. All pathways with a P < 0.05 are shown for pathway enrichment