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  1. Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are two omega-3 fatty acids that can be synthesized out of their precursor alpha-linolenic acid (ALA). FADS and ELOVL genes encode the desaturase and elo...

    Authors: Insaf Loukil, David M. Mutch and Mélanie Plourde
    Citation: Genes & Nutrition 2024 19:11
  2. Mitochondrial respiration complexes play a crucial function. As a result, dysfunction or change is intimately associated with many different diseases, among them cancer. The epigenetic, evolutionary, and metab...

    Authors: Eman M. Ragab, Abeer A. Khamis, Doaa M. El Gamal and Tarek M. Mohamed
    Citation: Genes & Nutrition 2024 19:10
  3. The role of inflammation in the aetiology of cancer is recognized. However, no study yet examined the association between an anti-inflammatory diet and cutaneous melanoma and explored whether it could be modif...

    Authors: Cristina Fortes, Simona Mastroeni, Lauretta Levati, Massimo Alotto, Francesco Ricci and Stefania D’Atri
    Citation: Genes & Nutrition 2024 19:9
  4. Evidences have shown that obesity is influenced by various factors, including various hormones such as thyroid hormones and the body’s metabolism rate. It seems that practical solutions such as weight loss die...

    Authors: Mohammad Hassan Sohouli, Ghazaleh Eslamian, Seyed Hossein Ardehali, Seyed Ahmad Raeissadat, Ghazaleh Shimi, Katayoun Pourvali and Hamid Zand
    Citation: Genes & Nutrition 2024 19:8
  5. A major revelation of genome-scale biological studies in the post-genomic era has been that two-thirds of human genes do not encode proteins. The majority of non-coding RNA transcripts in humans are long non-c...

    Authors: Fatemeh Yazarlou, Fatemeh Alizadeh, Leonard Lipovich, Roberta Giordo and Soudeh Ghafouri-Fard
    Citation: Genes & Nutrition 2024 19:5

    The Correction to this article has been published in Genes & Nutrition 2024 19:12

  6. The protein tyrosine phosphatase 1B (PTP1B) plays a crucial role in the development of insulin resistance. Aerobic training (AT) and vitamin D (Vit D) supplementation have been shown to individually improve gl...

    Authors: Kimya Khaledi, Rastegar Hoseini and Ahmad Gharzi
    Citation: Genes & Nutrition 2024 19:4
  7. Tocotrienol-rich fraction (TRF) has been reported to protect the heart from oxidative stress-induced inflammation. It is, however, unclear whether the protective effects of TRF against oxidative stress involve...

    Authors: Nur Aliah Natasha Md Shahrulnizam, Mohd Danial Mohd Efendy Goon, Sharaniza Ab Rahim, Sook Weih Lew, Siti Hamimah Sheikh Abdul Kadir and Effendi Ibrahim
    Citation: Genes & Nutrition 2024 19:3
  8. People with type 2 diabetes have a tenfold higher prevalence of hypomagnesemia, which is suggested to be caused by low dietary magnesium intake, medication use, and genetics. This study aims to identify the ge...

    Authors: Lynette J. Oost, Roderick C. Slieker, Marieke T. Blom, Leen M. ’t Hart, Joost G. J. Hoenderop, Joline W. J. Beulens and Jeroen H. F. de Baaij
    Citation: Genes & Nutrition 2024 19:2
  9. Obese patients have been found to be susceptible to iron deficiency, and malabsorption of dietary iron is the cause of obesity-related iron deficiency (ORID). Divalent metal transporter 1 (DMT1) and ferroporti...

    Authors: Yanru Zhang, Ruike Ding, Yulin Zhang, Jia Qi, Wenbin Cao, Lijun Deng, Lin Zhou, Yun Ye, Ying Xue and Enqi Liu
    Citation: Genes & Nutrition 2024 19:1
  10. Breastfeeding affects the growth and development of infants, and polyunsaturated fatty acids (PUFAs) play a crucial role in this process. To explore the factors influencing the PUFA concentration in breast mil...

    Authors: Wen-Hui Xu, Yi-Ru Chen, Hui-Min Tian, Yi-Fei Chen, Jia-Yu Gong, Hai-Tao Yu, Guo-Liang Liu and Lin Xie
    Citation: Genes & Nutrition 2023 18:16
  11. Previous observational studies have shown associations between vitamin Ds and FGIDS[Including irritable bowel syndrome(IBS) and functional dyspepsia(FD)]. However, the association is controversial and the caus...

    Authors: Senbao Xu, Qiuyan Luo, Jian He, Xiling Chen, Simin Li and Yang Bai
    Citation: Genes & Nutrition 2023 18:14
  12. Coffee is one of the most consumed beverages in the world, coffee consumption has been growing in the United States over the past 20 years. Periodontitis is defined by the pathologic loss of the periodontal li...

    Authors: Wan-Zhe Liao, Zhi-Yi Zhou, Zi-Kai Lin, Shuo-Jia Xie, Ya-Fang Zheng, Jun-Tao Wang, Jun-Huang Zheng, Hao-Kai Chen, Wu-Shu Chen and Xu-Guang Guo
    Citation: Genes & Nutrition 2023 18:13
  13. Age-related macular degeneration (AMD) is one of the major causes of vision loss. Early AMD needs to be taken seriously, but the causal effects of lipid biomarkers on early AMD remain unclear.

    Authors: Fen-Fen Li, Yuqin Wang, Lishuang Chen, Chong Chen, Qi Chen, Lue Xiang, Feng-Qin Rao, Li-Jun Shen, Qin-Xiang Zheng, Quanyong Yi and Xiu-Feng Huang
    Citation: Genes & Nutrition 2023 18:11
  14. Glycogen storage disease type Ia (GSDIa) is an inborn metabolic disorder caused by the deficiency of glucose-6-phospatase-α (G6Pase-α) leading to mitochondrial dysfunction. It remains unclear whether mitochond...

    Authors: Alessandro Rossi, Antonia Assunto, Carmen Rosano, Sara Tucci, Margherita Ruoppolo, Marianna Caterino, Francesca Pirozzi, Pietro Strisciuglio, Giancarlo Parenti and Daniela Melis
    Citation: Genes & Nutrition 2023 18:10
  15. The predominant source of alcohol in the diet is alcoholic beverages, including beer, wine, spirits and liquors, sweet wine, and ciders. Self-reported alcohol intakes are likely to be influenced by measurement...

    Authors: Marta Trius-Soler, Giulia Praticò, Gözde Gürdeniz, Mar Garcia-Aloy, Raffaella Canali, Natella Fausta, Elske M. Brouwer-Brolsma, Cristina Andrés-Lacueva and Lars Ove Dragsted
    Citation: Genes & Nutrition 2023 18:7

    The Correction to this article has been published in Genes & Nutrition 2023 18:9

  16. FOXO has long been associated with aging, exercise, and tissue homeostasis, but it remains unclear what the role is of the muscle FOXO gene in E against high-salt intake(HSI)-induced age-related defects of the...

    Authors: Deng-tai Wen, Ying-hui Gao, Jingfeng Wang, Shijie Wang, Qi Zhong and Wen-qi Hou
    Citation: Genes & Nutrition 2023 18:6
  17. Serine hydroxymethyltransferase 2 (SHMT2) catalyzes the reversible conversion of tetrahydrofolate (THF) and serine-producing THF-conjugated one-carbon units and glycine in the mitochondria. Biallelic SHMT2 varian...

    Authors: Joanna L. Fiddler, Jamie E. Blum, Katarina E. Heyden, Luisa F. Castillo, Anna E. Thalacker-Mercer and Martha S. Field
    Citation: Genes & Nutrition 2023 18:5
  18. Flavonoids may help ameliorate the incidence of the major causes of tumor-related mortality, such as pancreatic ductal adenocarcinoma (PDAC) and lung cancer, which are predicted to steadily increase between 20...

    Authors: Eman M. Ragab, Doaa M. El Gamal, Tarek M. Mohamed and Abeer A. Khamis
    Citation: Genes & Nutrition 2023 18:4
  19. Metabotyping is a novel concept to group metabolically similar individuals. Different metabotypes may respond differently to dietary interventions; hence, metabotyping may become an important future tool in pr...

    Authors: Amanda Rundblad, Jacob J. Christensen, Kristin S. Hustad, Nasser E. Bastani, Inger Ottestad, Kirsten B. Holven and Stine M. Ulven
    Citation: Genes & Nutrition 2023 18:3
  20. Alzheimer’s disease (AD) is a progressive neurodegenerative disorder pathologically characterized by brain parenchymal abundance of amyloid-beta (Aβ) and the accumulation of lipofuscin material that is rich in...

    Authors: Zachary J. D’Alonzo, Virginie Lam, Ryu Takechi, Michael Nesbit, Mauro Vaccarezza and John C. L. Mamo
    Citation: Genes & Nutrition 2023 18:2
  21. Authors: Sahar Cheshmeh, Negin Elahi, Maysa Ghayyem, Elaheh Mosaieby, Shima Moradi, Yahya Pasdar, Susan Tahmasebi and Mehdi Moradinazar
    Citation: Genes & Nutrition 2023 18:1

    The original article was published in Genes & Nutrition 2022 17:17

  22. Polycystic ovary syndrome (PCOS) is an endocrine disease in which related to obesity, metabolic disorders and is considered as one of the main causes of infertility in women. This trial was investigated the ef...

    Authors: Sahar Cheshmeh, Negin Elahi, Maysa Ghayyem, Elaheh Mosaieby, Shima Moradi, Yahya Pasdar, Susan Tahmasebi and Mehdi Moradinazar
    Citation: Genes & Nutrition 2022 17:17

    The Correction to this article has been published in Genes & Nutrition 2023 18:1

  23. Prebiotic/probiotic supplementation represents a viable option for addressing elevated systemic inflammation and chronic disease risk in overweight individuals. The purpose of this study was to determine if 90...

    Authors: Brian K. McFarlin, Elizabeth A. Tanner, David W. Hill and Jakob L. Vingren
    Citation: Genes & Nutrition 2022 17:15
  24. Interactions between genetic, metabolic, and environmental factors lead to gestational diabetes mellitus (GDM). We aimed to examine interactive effects of cyclin-dependent kinase 5 regulatory subunit-associate...

    Authors: Hui Wang, Jing Li, Jinnan Liu, Junhong Leng, Weiqin Li, Zhijie Yu, Claudia H. T. Tam, Gang Hu, Ronald C. W. Ma, Zhongze Fang, Ying Wang and Xilin Yang
    Citation: Genes & Nutrition 2022 17:14
  25. Obesity is a serious disease with a complex etiology characterized by overaccumulation of adiposity resulting in detrimental health outcomes. Given the liver’s critical role in the biological processes that at...

    Authors: Phoebe Yam, Melissa VerHague, Jody Albright, Erik Gertz, Fernando Pardo-Manuel de Villena and Brian J. Bennett
    Citation: Genes & Nutrition 2022 17:13
  26. Phenylthiocarbamide (PTC) sensitivity, a sensory trait mediated by the bitter taste receptor 38 (TAS2R38), has been described as a promising biomarker of health status or disease risk. The aim of this cross-se...

    Authors: Marta Trius-Soler, Paz A. Bersano-Reyes, Clara Góngora, Rosa M. Lamuela-Raventós, Gema Nieto and Juan J. Moreno
    Citation: Genes & Nutrition 2022 17:12
  27. MicroRNAs (miRNAs) targeting has been revealed to be an appealing strategy for the treatment and management of atrial fibrillation (AF). In this research, we aimed to explore the mechanisms of miR-205-5p in re...

    Authors: Zezhou Xiao, Yu Xie, Fangze Huang, Jie Yang, Ximao Liu, Xuefeng Lin, Peng Zhu and Shaoyi Zheng
    Citation: Genes & Nutrition 2022 17:11
  28. The development of type 2 diabetes mellitus (T2DM) is highly influenced by complex interactions between genetic and environmental (dietary and lifestyle) factors. While vitamin C (ascorbic acid, AA) has been s...

    Authors: Chung-Lin Jiang, Chang-Yu Tsao and Yi-Ching Lee
    Citation: Genes & Nutrition 2022 17:10
  29. We examined the influence of superoxide dismutase 3 (SOD3) Arg213Gly and Peroxisome Proliferator-Activated α-Receptor (PPARα) 7G/C polymorphisms to a single dose of purple grape juice supplementation on time-t...

    Authors: Bruno Rafael Virginio de Sousa, Lydiane de Lima Tavares Toscano, Eder Jackson Bezerra de Almeida Filho, Klécia Farias Sena, Matheus Silveira Costa, Rebeka Correia de Souza Cunha, Jullyana de Souza Siqueira Quintans, Luana Heimfarth, Aline Telles Biasoto Marques, Darcilene Fiuza da Silva, Luis Felipe Castelli Correia de Campos, Darlene Camati Persuhn and Alexandre Sérgio Silva
    Citation: Genes & Nutrition 2022 17:9
  30. Early life vitamin D exposure is linked to later skeletal health with maternal vitamin D status in pregnancy associated with neonatal bone mass. The MAVIDOS study has demonstrated that vitamin D supplementatio...

    Authors: Nevena Krstic, Nick Bishop, Beth Curtis, Cyrus Cooper, Nick Harvey, Karen Lilycrop, Robert Murray, Robert Owen, Gwen Reilly, Tim Skerry and Steph Borg
    Citation: Genes & Nutrition 2022 17:7
  31. Genetic instability leads to genome mutations, changes in nucleotide sequences, rearrangements, and gains or losses of part of the chromosomes. This instability can initiate and develop cancer. This study eval...

    Authors: Abeer A. Khamis, Rana M. Ibrahim, Gad B. El-hefnawy, Wafaa M. Ibrahim and Ehab M. Ali
    Citation: Genes & Nutrition 2022 17:6
  32. Metabolic syndrome (MetS) is characterized by the coexistence of disorders such as diabetes, hypertension, hyperlipidemia, and obesity and is affected by genetic factors. Previous genome-wide association studi...

    Authors: Woo Jeong Choi and Dayeon Shin
    Citation: Genes & Nutrition 2022 17:5
  33. Cancer therapy targeting programmed death receptor-1 (PD-1 or CD279) or programmed death-ligand 1 (PD-L1 or CD274) gives hope to Tongue Squamous Cell Carcinoma (TSCC) treatment. However, the tumor-intrinsic me...

    Authors: Mingjing Peng, Songqing Fan, Junjun Li, Xiao Zhou, Qianjin Liao, Faqing Tang and Wei Liu
    Citation: Genes & Nutrition 2022 17:3
  34. Vitamin D (Vit-D) promotes vascular repair and its deficiency is closely linked to the development of type 2 diabetes mellitus (T2DM) and hypertension. Whether genetially predicted vitamin D status (serologica...

    Authors: Yap-Hang Chan, C. Mary Schooling, Jie V. Zhao, Shiu-Lun Au Yeung, Jo Jo Hai, G. Neil Thomas, Kar-Keung Cheng, Chao-Qiang Jiang, Yuen-Kwun Wong, Ka-Wing Au, Clara S. Tang, Chloe Y. Y. Cheung, Aimin Xu, Pak-Chung Sham, Tai-Hing Lam, Karen Siu-Ling Lam…
    Citation: Genes & Nutrition 2022 17:1
  35. Worldwide, the prevalence of obesity and insulin resistance has grown dramatically. Gene expression profiling in blood represents a powerful means to explore disease pathogenesis, but the potential impact of i...

    Authors: Marianthi Kalafati, Martina Kutmon, Chris T. Evelo, Carla J. H. van der Kallen, Casper G. Schalkwijk, Coen D. A. Stehouwer, B. I. O. S. Consortium, Ellen E. Blaak, Marleen M. J. van Greevenbroek and Michiel Adriaens
    Citation: Genes & Nutrition 2021 16:22
  36. Copy number (CN) variation (CNV) of the salivary amylase gene (AMY1) influences the ability to digest starch and may influence glucose homeostasis, obesity and gut microbiota composition. Hence, the aim was to ex...

    Authors: Mary Farrell, Stina Ramne, Phébée Gouinguenet, Louise Brunkwall, Ulrika Ericson, Anne Raben, Peter M. Nilsson, Marju Orho-Melander, Yvonne Granfeldt, Juscelino Tovar and Emily Sonestedt
    Citation: Genes & Nutrition 2021 16:21
  37. Circulating branched chain amino acids (BCAAs) increase the risk of type 2 diabetes (T2D). The genetic variants in the BCAA metabolic pathway influence the individual metabolic ability of BCAAs and may affect ...

    Authors: Weiqi Wang, Zengjiao Liu, Lin Liu, Tianshu Han, Xue Yang and Changhao Sun
    Citation: Genes & Nutrition 2021 16:20
  38. Until now, observational studies have explored the impact of vitamin C intake on Alzheimer’s disease (AD) risk, however, reported ambiguous findings. To develop effective therapies or prevention, the causal li...

    Authors: Haijie Liu, Yan Zhang, Yang Hu, Haihua Zhang, Tao Wang, Zhifa Han, Shan Gao, Longcai Wang and Guiyou Liu
    Citation: Genes & Nutrition 2021 16:19

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