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Table 5 Iron deficiency: down-regulated (A) and up-regulated (B) sequences in fatty acids and cholesterol metabolic pathways

From: Molecular bases of copper and iron deficiency-associated dyslipidemia: a microarray analysis of the rat intestinal transcriptome

 

Fold induction

A

 Apoh

Apolipoprotein H

−20.35

 Pla2g4a

Phospholipase A2, group IVA

−2.80

 Cd36

cd36 antigen

−2.29

 Prkaa1

Protein kinase, AMP-activated, alpha 1 subunit

−1.88

 Lypla1

Lysophospholipase 1

−1.84

 Edg2

Endothelial differentiation, G-protein coupled recap.

−1.75

 Plaa

Phospholipase A2, activating protein

−1.73

 Plscr1

Phospholipid scramblase 1

−1.70

 Acsl3

Acyl-CoA synthetase long-chain family member 3

−1.59

 Idi1

Isopentenyl-diphosphate delta isomerase

−1.57

 Scp2

Sterol carrier protein 2

−1.56

 Anxa1

Annexin A1

−1.56

 Acsl1

Acyl-CoA synthetase long-chain family member 1

−1.47

 Pitpn

Phosphatidylinositol transfer protein

−1.44

 Cd1d1

CD1d1 antigen

−1.34

 Scd2

Stearoyl-coenzyme A desaturase 2

−1.27

 Cds1

CDP-diacylglycerol synthase 1

−1.25

 Cnbp1

Cellular nucleic acid binding protein 1

−1.26

 Cdipt

CDP-diacylglycerol-inositol3-phosphatidyltransferase

−1.22

 Pctp

Phosphatidylcholine transfer protein (Pctp), mRNA.

−1.22

B

 Dgka

Diacylglycerol kinase, alpha (80 kDa)

1.22

 Clps

Colipase, pancreatic

1.27

 Cel

Carboxyl ester lipase

1.30

 Fabp6

Fatty acid binding protein 6 (gastrotropin)

1.31

 Pnliprp1

Pancreatic lipase-related protein 1

1.32

 Pmvk

Phosphomevalonate kinase

1.32

 Fabp2

Fatty acid binding protein 2, intestinal

1.32

 Pnlip

Pancreatic lipase

1.33

 Pla2g1b

Phospholipase A2, group IB

1.38

 Mvd

Mevalonate (diphospho) decarboxylase

1.38