APOB-516 T allele homozygous subjects are unresponsive to dietary changes in a three-month primary intervention study targeted to reduce fat intake

Table 1 Dietary parameters: comparison between genders

Subjects	Men (n = 69)		Women (n = 100)		P value^e
Subjects	Mean ± SD	% tot energy	Mean ± SD	% tot energy	P value^e
Total energy (kJ/kg bw)
Baseline	112.8 ± 40.7		103.6 ± 30.0		0.090
3 months	84.5 ± 31.7*		77.4 ± 21.5*		0.601
CHO (g/kg bw)^a
Baseline	2.79 ± 1.0	39.8 ± 7.34	2.6 ± 0.91	41.8 ± 6.79	0.162
3 months	2.30 ± 0.83*	43.2 ± 6.70	2.1 ± 0.67*	45.2 ± 5.97	0.993
Total protein (g/kg bw)
Baseline	1.23 ± 0.30	17.7 ± 3.1	1.12 ± 0.31	18.5 ± 3.60	0.029
3 months	1.02 ± 0.28*	19.67 ± 3.8	0.91 ± 0.24*	19.9 ± 2.97	0.985
Total fat (g/kg bw)
Baseline	1.18 ± 0.43	37.2 ± 6.0	1.05 ± 0.39	37.7 ± 6.4	0.038
3 months	0.78 ± 0.24*	32.2 ± 5.6	0.69 ± 0.23*	33.5 ± 5.6	0.476
SFA (g/kg bw)^b
Baseline	0.44 ± 0.20	13.8 ± 3.5	0.38 ± 0.17	13.7 ± 3.7	0.042
3 months	0.23 ± 0.08*	9.7 ± 2.8	0.21 ± 0.09*	10.1 ± 2.8	0.129
MUFA (g/kg bw)^c
Baseline	0.43 ± 0.15	13.7 ± 2.6	0.39 ± 0.15	13.9 ± 3.5	0.063
3 months	0.33 ± 0.11*	14.2 ± 3.4	0.29 ± 0.11*	14.3 ± 3.9	0.874
PUFA (g/kg bw)^d
Baseline	0.15 ± 0.07	5.04 ± 1.95	0.15 ± 0.08	5.30 ± 2.10	0.609
3 months	0.14 ± 0.06	5.84 ± 2.02	0.12 ± 0.07*	5.85 ± 2.88	0.361

Values in bold denote significant value for P
* P < 0.05 for comparison between baseline and after the diet period
^aCHO, carbohydrates (g/kg body weight)
^bSFA, saturated fatty acids (g/kg body weight)
^cMUFA, monounsaturated fatty acids (g/kg body weight)
^dPUFA, polyunsaturated fatty acids (g/kg body weight)
^eComparison between men and women at baseline (tested with general linear models) and in their three-month response to diet (tested with repeated measures general linear models) calculated from raw data (g/kg body weight)

ISSN: 1865-3499