Fig. 7

Risk of upper aerodigestive cancer by ADH1B genetic variation, stratified by drinking intensity and smoking status. Odds ratio (OR) of upper aerodigestive cancer by re1229984 (ADH1B). Rare allele (dominant model) carriers versus common allele homozygous genotype. ORs are standardised by age, sex, center, cumulative alcohol consumption and, when relevant, smoking. ORs and 95% CI are derived from fixed effects models. Source: Hashibe et al. [78]