Table 2 Changes in blood parameters after the energy-restricted (ER) intervention (mean ± SD is presented)
Treatment | Lean (n = 15) | Obese (n = 17) | p value# | ||
|---|---|---|---|---|---|
Before ER | After ER | Before ER | After ER | ||
Glucose (mmol/L) | 5.4 ± 0.3 | 5.5 ± 0.3 | 5.7 ± 0.3 | 5.7 ± 0.4 | N.S. |
Insulin (mU/L) | 5.9 ± 3.3 | 5.0 ± 2.7 | 12.7 ± 6.1 | 11.0 ± 6.8 | N.S. |
HbA1c (%) | 5.1 ± 0.2 | 5.0 ± 0.2 | 5.1 ± 0.2 | 5.0 ± 0.1 | <0.05 |
Total cholesterol (mmol/L) | 5.2 ± 0.7 | 4.7 ± 0.7 | 6.0 ± 0.7 | 5.4 ± 0.5 | <0.05 |
HDL-cholesterol (mmol/L) | 1.3 ± 0.4 | 1.3 ± 0.3 | 1.2 ± 0.2 | 1.1 ± 0.2 | N.S. |
LDL-cholesterol (mmol/L) | 3.3 ± 0.6 | 2.9 ± 0.6 | 3.9 ± 0.6 | 3.5 ± 0.4 | <0.05 |
Ratio cholesterol/HDL | 4.3 ± 1.2 | 3.8 ± 0.9 | 5.3 ± 0.9 | 4.9 ± 0.9 | <0.05 |
Triacylglycerol (mmol/L) | 1.4 ± 0.7 | 1.1 ± 0.5 | 2.2 ± 1.2 | 2.1 ± 1.4 | N.S. |
γ-GT (U/L) | 23.4 ± 11.2 | 18.2 ± 8.0 | 33.9 ± 12.8 | 27.5 ± 12.5 | <0.05 |
ALAT (U/L) | 12 ± 4 | 12 ± 4 | 19 ± 11 | 19 ± 11 | N.S. |
ASAT (U/L) | 21 ± 4 | 20 ± 4 | 26 ± 8 | 24 ± 6 | + |
ALP (U/L) | 64 ± 12 | 60 ± 10 | 67 ± 18 | 65 ± 14 | N.S. |
TNF-α (pg/mL)a | 0.97 ± 0.29 | 0.88 ± 0.18 | 1.08 ± 0.34 | 1.11 ± 0.39 | N.S. |