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Table 4 Metabolite concentrations and nutrient intakes between SAM/SAH clusters

From: Methylation potential associated with diet, genotype, protein, and metabolite levels in the Delta Obesity Vitamin Study

 

Cluster 1

Cluster 2

p value

Metabolite

   

 SAM/SAH

1.81 ± 0.48

1.61 (1.41–2.95)

(n = 10)

0.81 ± 0.28

0.79 (0.31–1.31)

(n = 51)

<0.001

 SAM (nmol/ml)

1.44 ± 0.31

1.34 (1.1–1.95)

(n = 10)

0.77 ± 0.28

0.73 (0.34–1.59)

(n = 51)

<0.001

 SAH (nmol/ml)

0.88 ± 0.14

0.87 (0.63–1.15)

(n = 10)

0.96 ± 0.11

0.95 (0.7–1.31)

(n = 51)

0.022

 Homocysteine (µmol/l)

11.1 ± 4.0

11.9 (5.6–17.5)

(n = 10)

7.3 ± 2.8

6.2 (3.5–14)

(n = 51)

0.053

 Vitamin A (µg/dl)

98 ± 35

93 (36–156)

(n = 8)

61 ± 27

56 (11.5–134)

(n = 42)

0.038

Intake variable

   

 Energy intake/BW (kcal/kg)

67.1 ± 29.5

64.4 (22–112)

(n = 10)

46.0 ± 18.7

41.4 (16.0–102.9)

(n = 51)

0.009

 Thiamin intake (mg/day)

1.50 ± 0.59

1.4 (0.83–2.5)

(n = 10)

1.30 ± 0.40

1.3 (0.59–2.2)

(n = 51)

0.013

 Iron intake (mg/day)

12.9 ± 3.4

11.6 (9.5–19)

(n = 10)

10.9 ± 3.4

10.5 (5.4–23.2)

(n = 51)

0.041

 β-Carotene intake (mcg/d)

1,539 ± 2,718

456 (139–8,676)

(n = 10)

787 ± 1,072

381 (30–4,339)

(n = 51)

0.027

 Vitamin A intake (RE) (mcg/day)

518 ± 340

438(200–1,328)

(n = 10)

420 ± 170

370 (125–885)

(n = 51)

0.034

  1. Analyses as per methods. Differences in other metabolites between clusters did not reach statistical significance