| Responders (n = 8) | Non-responders (n = 16) |  |  | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Baseline | Change 7 weeks |  | Baseline | Change 7 weeks |  | P ‡ | P ‡ | |||||||||
Median/n | 25th | 75th | Median | 25th | 75th | P †| Median/n | 25th | 75th | Median | 25th | 75th | P †| Baseline | Δ 7 weeks | |
Gender (male/female) | 3/5 |  |  |  |  |  |  | 5/11 |  |  |  |  |  |  | 1§ |  |
Intervention group (FO/oxFO) | 2/6 |  |  |  |  |  |  | 10/6 |  |  |  |  |  |  | 0.19§ |  |
Age (years) | 23.5 | 21.5 | 25.8 | Â | Â | Â | Â | 26.5 | 22.5 | 33 | Â | Â | Â | Â | 0.17 | Â |
BMI (kg/m2) | 22.4 | 21.2 | 22.9 | Â | Â | Â | Â | 22.0 | 21.2 | 23.6 | Â | Â | Â | Â | 0.98 | Â |
Biochemical parameters | ||||||||||||||||
 Total-C (mM) | 4.6 | 4.1 | 5.0 | 0.0 | − 0.3 | 0.4 | 1 | 4.8 | 4.4 | 5.2 | 0.1 | − 0.2 | 0.3 | 0.8 | 0.5 | 0.9 |
 LDL-C (mM) | 2.4 | 2.0 | 3.1 | 0.2 | − 0.3 | 0.5 | 0.5 | 2.8 | 2.3 | 3.1 | 0.1 | − 0.2 | 0.2 | 0.8 | 0.7 | 0.6 |
 HDL-C (mM) | 1.3 | 1.2 | 1.5 | 0.0 | − 0.1 | 0.1 | 0.7 | 1.3 | 1.3 | 1.6 | 0.0 | 0.0 | 0.1 | 0.2 | 0.4 | 0.8 |
 TG (mM) | 1.5 | 1.4 | 1.7 | − 0.6 | − 0.6 | − 0.5 | 0.01* | 0.8 | 0.7 | 1.1 | 0.0 | 0.0 | 0.0 | 0.6 | 0.01* | 0.0001* |
 Glucose (mM) | 4.7 | 4.7 | 4.8 | 0.0 | − 0.1 | 0.4 | 0.5 | 4.6 | 4.5 | 5.0 | 4.8 | 4.6 | 5.1 | 0.2 | 0.9 | 1 |
 18:1 n-9 (OA) (wt%) | 24.74 | 21.40 | 26.09 | − 3.86 | −  5.51 | − 2.25 | 0.01* | 19.18 | 18.28 | 20.35 | − 0.81 | − 1.92 | −  0.03 | 0.01* | 0.007* | 0.004* |
 18:2 n-6 (LA) (wt%) | 25.34 | 23.31 | 26.78 | 0.94 | − 0.58 | 3.22 | 0.5 | 32.12 | 29.77 | 33.41 | − 1.59 | − 2.78 | 0.59 | 0.04* | 0.009* | 0.04* |
 18:3 n-3 (ALA) (wt%) | 0.71 | 0.52 | 0.76 | − 0.23 | − 0.34 | −  0.04 | 0.01* | 0.57 | 0.52 | 0.63 | − 0.05 | −  0.14 | 0.01 | 0.1 | 0.3 | 0.03* |
 20:4 n-6 (AA) (wt%) | 6.30 | 5.68 | 6.45 | 0.01 | − 0.25 | 0.16 | 1 | 6.20 | 5.62 | 7.05 | − 0.54 | − 1.29 | − 0.38 | 0.0004* | 0.9 | 0.01* |
 20:5 n-3 (EPA) (wt%) | 0.50 | 0.44 | 0.70 | 1.90 | 1.79 | 2.27 | 0.01* | 0.69 | 0.53 | 0.82 | 2.08 | 1.41 | 2.41 | 0.0005* | 0.3 | 0.9 |
 22:5 n-3 (DPA) (wt%) | 0.42 | 0.37 | 0.61 | 0.15 | 0.11 | 0.24 | 0.01* | 0.53 | 0.47 | 0.58 | 0.15 | 0.13 | 0.25 | 0.0009* | 0.6 | 0.9 |
 22:6 n-3 (DHA) (wt%) | 1.70 | 1.46 | 2.01 | 2.35 | 1.57 | 2.67 | 0.01* | 2.15 | 1.74 | 2.35 | 1.67 | 1.19 | 2.34 | < 0.0001* | 0.4 | 0.1 |
 omega-3 index (wt%) | 4.6 | 4.5 | 4.9 | 2.9 | 2.25 | 3.25 | 0.02* | 5.6 | 4.9 | 6.0 | 2.35 | 1.38 | 3.03 | 0.0004* | 0.03* | 0.2 |