Fig. 4From: Paternal high-fat diet altered SETD2 gene methylation in sperm of F0 and F1 micePaternal HFD altered methylation profile of SETD2 promoter region in F1 sperm. Methylation levels of the 26 sites in F1 sperm by pyrosequencing followed by principal component analysis (A) and heatmap analysis (B). Methylation level of Seq1 (C), Seq2 (D) and Seq3 (E) F1 sperm between the two groups. * above the bars indicates P < 0.05Back to article page