Fig. 4
From: Tracing vitamins on the long non-coding lane of the transcriptome: vitamin regulation of LncRNAs
Molecular pathways and axes in human disease, inferred from the published literature coupling the vitamin D / VDR pathway to long noncoding RNAs (lncRNAs). Since 1,25(OH)2D3 can affect intracellular pathways via different VDR or/and non-VDR partners, we categorize the pathways into those that are suggested after treatment with 1,25(OH)2D3 (A, the top left), those that focused on VDR itself (B, induction or gene expression assessments) (top right), and those that jointly evaluated the effect of 1,25(OH)2D3 treatment and VDR at the same time (C, bottom). See Table 3 for details. CRC: Colorectal cancer; DM: Diabetes Mellitus. Created with BioRender.com